The human immune system is the extraordinary biochemical network responsible for keeping us well. As our molecular interface with the environment, it has evolved complex interactions with the plant world.

Mushrooms, which form one of the most primitive plant groups, have been valued for decades by progressive medical practitioners as immunopotentiators. Only recently, however, has science identified and tested the specific mushroom nutrients that augment natural defenses. AHCC® (active hexose correlated compound) is a proprietary mushroom compound. It is wellresearched in Japan for its immune-supportive properties, in particular the ability to increase natural killer cell and macrophage activity. Hundreds of Japanese hospitals and clinics recommend AHCC as part of an immune maintenance regimen, and its potent effects are so highly regarded that sales exceed $200 million dollars per year.

AHCC®: A Unique Compoundbr AHCC, or “active hexose correlated compound,�Eis a rich source of polysaccharides (beta glucan 1,3 and activated hemicellulose) and glycoproteins, plus amino acids and minerals. It is produced by enzymatic modification of several types of medicinal mushrooms, including shiitake. AHCC is derived from organically cultivated mushroom mycelia (the rich pre-mushroom stage, a network of fibrous filaments plus the medium it lives on and uses for fuel). The low molecular weight of AHCC makes it easier to absorb.

Your trillions of cells are susceptible to damage by free radicals and toxins, so a healthy immune system uses its first line of defense—natural killer (NK) cells—to quickly identify and destroy threatening particles. The effectiveness of NK cells depends on their activity level, so boosting NK activity is a smart strategy for those committed to maintaining vibrant health and longevity. AHCC is a potent biological response modifier that may significantly increase activity of NK cells and macrophages, according to human and animal studies. Literally “large things that devour,�Emacrophages are white blood cells that engulf and aid in the removal of foreign particles.

Cytokine Production Studies show AHCC also enhances production of cytokines, including interferons and interleukins. These intercellular chemical messengers trigger white blood cell production and activity. In one recent study, AHCC was shown to support normal basal levels of two cytokines, as well as NK activity. It is rare for a natural compound to have such a profound impact on strengthening the immune system.

Your liver is your body’s chemical manufacturing and detoxification factory. It must handle the full brunt of assault from environmental contaminants and pharmaceuticals. Stress further burdens this overworked organ. Human studies suggest AHCC supports healthy liver function.