Supplementspot's price for SAM-e is unprecedented for USP quality, enteric-coated SAM-e. Quality SAM-e is now affordable in the dosage that clinical studies show is necessary.

In 2002, the U.S. Department of Health released a study declaring SAM-e's benefits are equal to or better than prescription anti-depressants WITHOUT the SIDE-EFFECTS.

NOTE: If you are presently using SAM-e, you must be informed that ALL studies on this amazing natural substance show it must be taken in far larger doses than distributors such as Natrol, Sundown, Rexall will admit. As it is expensive to produce, they have led people to believe that 200 mg a day is effective. That is NOT true. Supplementspot's medical research experts have made a complete search of the record of ALL the published clinical trials demonstrating SAM-e effective in the treatment of arthritis and depression. Without exception, these clinical trials show SAM-e to be effective only if taken AT LEAST 400 to as much as 1600 mg per day (1-4 400 mg tablets). Any lesser amount and SAM-e is NOT biologically effective.

PLEASE NOTE: Much of the SAMe being sold does not meet scientifically accepted standards. The SAM-e molecule has two forms, one is the SS isomer (known as the active isomer) and the other is the RS isomer (known as the inactive isomer). All SAME-e contains percentages of both. The accepted levels for potency of SAM-e require a minimum of 70% SS(active) isomer content. Supplementspot's SAM-e tests at 74% or higher. Most manufacturers use 50% or even less active isomer content. Consumer Labs tested 30 preparations of SAME-e and only 4 had the acceptable "active ion" SAM-e content.

Buying a single bottle of SAM-e each month is NOT going to do you much good. You should buy 5 bottles (150 tablets) for a single month's supply and that is why we have reduced the price to just 0.93 a 400mg tablet ( when you buy 5 or more bottles) -- normal retail price is $1.85 or more--, or a month's supply of 150 tablets for $140. Expensive, but less than 1/2 the normal retail price for SAM-e.

(S-adenoslmethionine) is a naturally occurring compound found in all living organisms. In humans, SAM-e is distributed throughout the body and is involved in many important biochemical reactions. SAM-e is critical in the maintenance of cartilage and in the manufacture of important brain compounds such as neurotransmitters.

Because significant amounts of SAM-e are not readily available through the diet, the body is responsible for making its own SAM-e. Scientists know that certain groups of people, including the elderly, have low levels of SAME-e in their bodies. For many reasons, it is important to maintain proper levels of SAM-e in the body. Numerous clinical studies involving tens of thousands of people indicate that supplementation with SAM-e supports and promotes the health of a multitude of body functions.

SAM-e is popular in Europe where doctors have administered it for over 20 years. The benefits of SAM-e have been demonstrated by its long-term commercial use there. SAM-e is now available in the US mass market as a dietary supplement. Short and long term clinical studies show that SAM-e is a very safe and non-toxic product in levels of supplementation of up to 2,600 mg a day.*

SAM-e tablets made to Supplementspot's guaranteed purity and potency standards.

Our SAM-e product is the highest potency, most scientifically advanced and most highly stabilized SAM-e product available today!

Our enteric coating process is of the latest technology. It is enteric matrix coated, (Each tiny particle is enteric coated) then it is formed into a convenient caplet form. This unique process assures you of the maximum shelf life and the full freshness of this food to be as close as possible as when it was processed.

Clinical studies demonstrate that one must take AT LEAST 1-2 tablets (400 - 800 mg) a day in order to enjoy the benefits of SAM-e. Less may be biologically useless. It is best to take SAM-e with a glass of water and food. Depending on the condition, some people may achieve additional benefits with a higher level of supplementation up 1,600 mg a day.

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